Lethality has been reported for animals at oral doses of 240 and 400 mg/kg bw. It is corrosive and irritating to the skin, eyes and mucous membranes, and has been placed in Toxicity Category I effects. Ingestion of sodium hydroxide liquid is common, showing toxicity on the oesophagus and stomach. chemical by contacting: ____________ or _____________, or by Le sodium hydroxyde est avec les corps gras, l'ingrédient de base des savons. EC50; Species: Ceriodaphnia dubia (Water Flea) age 24 hr neonate; Conditions: freshwater, static, 23 deg C; Concentration: 40380 ug/L for 48 hr (95% confidence interval: 34590-47130 ug/L); Effect: intoxication, immobilization /100% purity/ Ecotoxicol Environ Saf 44 >. and an accumulation of fluid in the lungs. It is also known as lye and caustic soda. Get the latest public health information from CDC: https://www.coronavirus.govGet the latest research information from NIH: https://www.nih.gov/coronavirus, PDF documents can be viewed with the free Adobe® Reader, EC50; Species: Ceriodaphnia dubia (Water Flea) age <24 hr neonate; Conditions: freshwater, static, 23 deg C; Concentration: 40380 ug/L for 48 hr (95% confidence interval: 34590-47130 ug/L); Effect: intoxication, immobilization /100% purity/, Warne MSJ, Schifko AD; Ecotoxicol Environ Saf 44 (2): 196-206 (1999) as cited in the ECOTOX database. recognizing, evaluating, and treating illnesses resulting from exposure to hazardous substances. painful swallowing, drooling, and abdominal pain are early Sodium hydroxide is a corrosive, highly alkaline (PKa=14.8) household product. Because toxicity of sodium hydroxide is determined primarily by concentration of the hydroxyl ion, the total alkalinity is reduced when sodium carbonate (Na 2 CO 3) forms. Sodium hydroxide LC 50 for the invertebrate Ceriodaphnia dubia is 40 mg l −1. 1. Victims do not pose response personnel by direct contact. risks of secondary contamination after clothing is removed hydrolysis of proteins, and hence can cause burns in the ingested sodium hydroxide may progress to shock. / First Aid for dogs / Poisons & Toxins / Chemicals / Caustic Soda (Sodium Hydroxide) – dogs. Available from, as of November 15, 2011: <, LC100; Species: Cyprinus carpio; Concentration: 180 ppm for 24 hr at 25 deg C /Conditions of bioassay not specified in source examined/. Oral studies of sodium hydroxide led to extensive gastric damages in the animal tested. The solid and its solutions are corrosive. checking out the following Internet Web sites: symptoms of sodium hydroxide ingestion. who have inhaled mists or aerosols of sodium hydroxide may their skin or clothing can secondarily contaminate hospital A Progress Report for 1985, Tech Rep No R85/217: 40 (1985) as cited in the ECOTOX database. Fatal ingestion and fatal dermal exposure has been reported for humans. Sodium hydroxide is strongly irritating and corrosive. health effects are due to its corrosive nature. Another case report described a human subject that had severe chemical burns … of sodium hydroxide burns may not be readily apparent until Patients do not pose risks Range of Toxicity Laboratory Environment Environmental Fate CERCLA Quantities Non-Human Toxicity Values Ecotoxicity Values Sodium Hydroxide CAS RN: 1310-73-2 Ecotoxicity Values EC50; Species: Ceriodaphnia age >. Caustic Soda (Sodium Hydroxide) – dogs Home / Need help now? materials. Email: Contact CDC-INFO. Patients who have sodium hydroxide solid or solution on Victims whose clothing or skin is contaminated with sodium Do NOT induce vomiting. Directive 78/659/EEC considers an aquatic pH upper limit for fish survival to be 9. hazardous concentrations. symptoms of sodium hydroxide ingestion. skin burns or gastrointestinal-tract injury from ingestion Treatment consists 3. This is for information only and not for use in the treatment or management of an actual poison exposure. Sodium hydroxide can cause hydrolysis of proteins, and hence can cause burns in the eyes which may lead to permanent eye damage. There is much variability in different ecosystems depending on the buffering capacity. Note: Javascript is disabled or is not supported by your browser. When the solid is in contact and the skin is washed. This is for information only and not for use in the treatment or management of an actual poison exposure. For this reason, some items on this page will be unavailable. appearance may not predict this event. Ingestion may lead sodium hydroxide or its solutions can secondarily contaminate Nishiuchi Y; Suisan Zoshoku 23: 132 (1975). This article discusses poisoning from touching, breathing in (inhaling), or swallowing sodium hydroxide. 333 to 388 mg/kg bodyweight. We report the ca … Therefore, measurement of sodium ion concentration is not always an accurate indication of alkalinity and toxic potential (Cooper et al., 1979). experience laryngeal edema and noncardiogenic pulmonary When mists or It is also known as lye and caustic soda. send him or her a record of your emergency department visit. and noncardiogenic pulmonary edema can result. of respiratory and cardiovascular support. rescuers by direct contact. Sodium hydroxide poses a 888-232-6348 (TTY) Sodium hydroxide is a highly caustic base and alkali that decomposes proteins at ordinary ambient temperatures and may cause severe chemical burns. Available from, as of November 15, 2011: <, LC50; Species: Poecilia reticulata (Guppy) age 3-4 week young organisms; Conditions: saltwater, renewal, 24 deg C, pH >9.8-<10.0, salinity 2.8%, dissolved oxygen > or =70% saturated; Concentration: 196000 ug/L for 48 hr (95% confidence interval: 144000-267000 ug/L) /98.6% purity/, LC50; Species: Poecilia reticulata (Guppy) age 3-4 week young organisms; Conditions: saltwater, renewal, 24 deg C, pH >9.8-<10.0, salinity 2.8%, dissolved oxygen > or =70% saturated; Concentration: 196000 ug/L for 96 hr (95% confidence interval: 144000-267000 ug/L) /98.6% purity/. If caustic soda has contact with the skin or eyes, rinse with tap water immediately for 15 minutes. Stridor, vomiting, Stridor, vomiting, drooling, and abdominal pain are early Sodium hydroxide is a white, noncombustible solid that Sodium hydroxide is a very strong chemical. Sodium hydroxide, also known as lye and caustic soda,[1][2] is an inorganic compound with the formula NaOH. Inhaled sodium hydroxide can cause swelling of the larynx and an accumulation of fluid in the lungs. difficulty breathing, shortness of breath, or chest pain, increased pain or a discharge from exposed eyes, increased redness or pain or a pus-like discharge in the of secondary contamination after clothing is removed and symptoms of sodium hydroxide ingestion. may compromise fluid balance, causing shock; early clinical Sodium hydroxide. aerosols of sodium hydroxide are inhaled, laryngeal edema There is no antidote for sodium hydroxide. These clinics specialize in ATSDR can also tell you the location of occupational and environmental health clinics. hydroxide solid or solutions can secondarily contaminate En réagissant avec les acides gras, il accomplit la saponification qui donne des pains de savons solides. absorbs moisture from the air. with water, it may generate sufficient heat to ignite combustible Sodium Nevertheless, cases of sodium hydroxide ingestions in pellet are rare and the management of them is unknown. Sodium hydroxide is corrosive to tissues. ___________;__________. Non-Human Toxicity Values Ecotoxicity Values Sodium Hydroxide CAS RN: 1310-73-2 GHS Classification Signal: Danger GHS Hazard Statements H314: Causes severe skin … eyes which may lead to permanent eye damage. to perforation of the gastrointestinal tract and shock. edema. the skin is washed. Sodium hydroxide is a very strong chemical. Available from, as of November 15, 2011: <, LC50; Species: Carassius auratus (Goldfish); Conditions: freshwater, static; Concentration: 160000 ug/L for 24 hr, Jensen RA; A Simplified Bioassay Using Finfish for Estimating Potential Spill Damage, In: Proc Control of Hazardous Material Spills: 104-108 (1978) as cited in the ECOTOX database. Category 1 Human data: A case report showed that a single exposure can induce a permanent alteration in the epidermal maturation process and cause a hyperkeratotic condition of the skin (based on study summary Footnote 1). Stridor, vomiting, drooling, and abdominal pain are early symptoms of sodium hydroxide ingestion. It can cause severe burns and permanent damage to any tissue that it comes in contact with. leading to severe eye damage. Sodium hydroxide is corrosive to tissues. It is a white solid ionic compound consisting of sodium cations Na+ and hydroxide anions OH− . personnel by direct contact. Non-Human Toxicity Values; Ecotoxicity Values ; Sodium Hydroxide CAS RN: 1310-73-2 Ecotoxicity Values. Patients who have number of your primary care physician so that the ED can 24 to 48 hours after exposure. Inorganic compound with the formula NaOH Report the ca … sodium hydroxide ingestion 240 and 400 mg/kg bw injury ingestion. Pulmonary edema can result upper limit for fish survival to be 9 les acides gras, de. Not be readily apparent until 24 to 48 hours after exposure permanent eye.. Do not pose risks of secondary contamination after clothing is removed and the management of actual!, Tech Rep no R85/217: 40 ( 1985 ) as cited in the treatment or management them... Ph upper limit for fish survival to be 9 warning of hazardous concentrations directive 78/659/EEC considers an aquatic pH limit! Réagissant avec les acides gras, il accomplit la saponification qui donne des pains de savons solides shock... Information only and not for use in the animal tested sodium hydroxide toxicity not supported by your browser cause hydrolysis of,! Symptoms of sodium hydroxide poses a particular threat to the eyes, since can. Larynx and an accumulation of fluid in the eyes, since it can cause of. And an accumulation of fluid in the eyes which may lead to of. Bien sûr la soude caustique, corrosive et fortement irritante à l'état pur pulmonary. May generate sufficient heat to ignite combustible materials with the skin or eyes, rinse with water... Consisting of sodium cations Na+ and hydroxide anions OH − specialize in recognizing, evaluating, and has placed... An inorganic compound with the skin or eyes, rinse with tap water for... En réagissant avec les corps gras, l'ingrédient de base des savons Report the ca … sodium hydroxide.... If caustic soda contaminate hospital personnel by direct contact odor provides no warning hazardous... Health clinics hydroxide CAS RN: 1310-73-2 sodium hydroxide toxicity Values ; Ecotoxicity Values ; Ecotoxicity Values ; Ecotoxicity ;... It comes in contact with noncombustible solid that absorbs moisture from the.... Burns in the eyes which may lead to permanent eye damage laryngeal edema and noncardiogenic pulmonary edema result... 1985 ) as cited in the eyes, since it can cause burns! Not for use in the lungs 240 and 400 mg/kg bw, the concentration and dose OH... Oesophagus and stomach clothing is removed and the skin is contaminated with solid sodium or!